Frame-Switching: The Hidden Pattern in Pointless Arguments

The One-Inch Frame Two friends argue heatedly about whether a hot dog is a sandwich. One insists it is—bread on both sides, filling in the middle. The other insists it isn't—ask any deli. After twenty minutes, neither has moved an inch. How to Disagree About Categories In March 2008, Paul Graham published "How to Disagree," … Continue reading Frame-Switching: The Hidden Pattern in Pointless Arguments

The Biotech Supply Chain Hiding in Plain Sight

Response to: Yang, Y. Tony. "China's Beautiful Biotech Chaos vs West's Elegant Paralysis." Asia Times, December 28, 2025. https://asiatimes.com/2025/12/chinas-beautiful-biotech-chaos-vs-wests-elegant-paralysis/. Here's a statistic that should end the "race" metaphor: one-third of all Western Big Pharma acquisitions now originate from Chinese laboratories. The chaotic experimentation happens in Shanghai; the billion-dollar validation checks are signed in New York. The Global … Continue reading The Biotech Supply Chain Hiding in Plain Sight