It is of course famously difficult to say exactly what happens in [Philip K Dick’s The Three Stigmata of Palmer Eldritch], because the essential question that the major characters have is always: What is actually happening? But at least one major potential timeline, perhaps the most likely timeline, tells a story like this: Palmer Eldritch is a titan of capitalism, in many respects the Jeff Bezos of this world, and he travels to Proxima Centauri on a quest that is ambiguous in character but certainly involves financial motives. Eldritch discovers on Proxima Centauri a substance that the sentient beings of that solar system use in their religious rituals — a substance he thinks he can manufacture and sell and thereby win a victory over the currently dominant corporation called PP Layouts. But on his return from the Proxima system he is — well, perhaps the word is possessed by a sentient creature from some other part of the galaxy. And this creature is at least for a time interested in distributing its consciousness, through the mediation of Palmer Eldritch and the substance he has discovered, into the consciousness of human beings…
…Of course, this is not the only possible explanation of what is happening in the book. It is certainly possible that there is no alien being possessing Palmer Eldritch; rather, Eldritch himself has, through a combination of economic leverage and biotechnology, assumed equivalent powers. That is, it may be possible for surveillance capitalism to generate its own demons. Whether this is a better or worse fate than the one I previously described I leave as an exercise for the reader.”-Alan Jacobs, “It’s Palmer Eldritch’s world, we’re just living in it.” ayjay.org. April 8, 2021.
Given the choice between being possessed by demons from some other culture or possessed by demons generated from one’s own, both are bad options, and your answer is probably determined by how much novelty you prefer. I think the more interesting question is whether you’d rather be possessed by a demon or become one yourself. Neitzsche hits on the point:
““Beware that, when fighting monsters, you yourself do not become a monster… for when you gaze long into the abyss. The abyss gazes also into you.”― Friedrich W. Nietzsche
Most people can’t imagine being (or that they are) a monster. So, this choice is really about one’s self-concept. Are you good? Then, you may be more willing to be possessed, so you aren’t responsible for acting like a monster. But, choosing to be a monster? The first casualty is conscience, and then the body count goes up from there. Still, it’s probably true most people, even good people, would rather be predator than prey. This fact probably explains a lot about the human condition.