"U.S. drug development cycle, which he says “always follows the 5/10/15 rule. For the first 5 years, companies hype new drugs; next 5 years all hidden side effects are exposed, leading to black-box warnings and class action lawsuits; in [the] last 5 years, the companies start dissing their own old drug as the patent runs … Continue reading Generalizing the 5/10/15 Rule for U.S. Drug Development, Or The Cycle of the New
Category: writing
Boxing Time & Losing
Over the course of writing this blog, I've come to view writing as an important activity, like meditation. And like meditation, I find my motivation comes in fits and spurts. One thing I found helpful with this site is the "don't break the chain" method. Simply create the expectation and the space that you will … Continue reading Boxing Time & Losing
Words & Phrases, 2022
no fixed address, homeless asphodel, Greek land of the dead bioreactor meat food's comforting inner cuddle pay-triots, money-grubbing grifters exploiting a nationalist cause the death of nuance axolotls, Mexican salamander mononymous moral holiday the holiday from history call of the void, wanting to jump from a high place, hit a guard rail det stora oväsendet, … Continue reading Words & Phrases, 2022
Spielen Macht Frei (Play Sets You Free)
"The Prussian model seeks to create a population for whom work, no matter how mind-numbing or back-breaking, is the only hope. That's why they try to inspire us with the promise of a freedom that will never come. When we keep play alive in our own lives, in the lives of our children, even if … Continue reading Spielen Macht Frei (Play Sets You Free)
Generational Communication Preferences
https://twitter.com/meantomyself/status/1603453513501229068?s=20&t=8hcdM8ipcTH3yLQOxY-msw Before mobile phones, there were landline phones. If it was someone far away, they would have to pay "long distance" charges in order to talk to you. If it were someone in the local area code, they could just come over. But, with a landline phone conversations tend to be short, and there is … Continue reading Generational Communication Preferences
One Fifth of U.S. Adults Have Limited Reading Comprehension
"Many counties that lack programs also double as hot spots of low adult literacy. These are primarily in the mountains of Appalachia, the Southern Black Belt, the Central Valley of California and along the Texas border with Mexico, but they exist throughout the nation. In about 500 American counties, nearly a third of adults struggle … Continue reading One Fifth of U.S. Adults Have Limited Reading Comprehension
Critical Ignoring as a Core Competence for Digital Citizens
"Abstract Low-quality and misleading information online can hijack people’s attention, often by evoking curiosity, outrage, or anger. Resisting certain types of information and actors online requires people to adopt new mental habits that help them avoid being tempted by attention-grabbing and potentially harmful content. We argue that digital information literacy must include the competence of critical … Continue reading Critical Ignoring as a Core Competence for Digital Citizens
Filter Failure & Critical Ignoring
"As important as the ability to think critically continues to be, we argue that it is insufficient to borrow the tools developed for offline environments and apply them to the digital world. When the world comes to people filtered through digital devices, there is no longer a need to decide what information to seek. Instead, … Continue reading Filter Failure & Critical Ignoring
What You Feed Grows
What you feed grows. Don't like something you see on the Internet or in your life? Ignore it. Responding is rewarding the behavior, which means you'll see more of it. Getting no response drives people that want attention to do something else. Give your attention to what you want more of.
Our 17th Wedding Anniversary
Celebrating our 17th wedding anniversary today. Possibly my wife's favorite band is The Fall. I asked how she came to like them – they can be a hard band to like – and she says, "I liked them immediately, same as how I liked you immediately." Sweet, but she probably has unusual taste. "You don't … Continue reading Our 17th Wedding Anniversary
Some Reflections on Twitter & WordPress: 2022
You may have noticed that I have been posting to cafebedouin less lately. It is partially because I have been more involved in using Twitter. Why? One thing I like about Twitter is that it is a larger, socially constructed version of the kind of thoughts that we have moment to moment. Reading the timeline … Continue reading Some Reflections on Twitter & WordPress: 2022
Documentation As Empathy
...Writing documentation is an exercise in empathy. We're not describing an objective reality - the source code already does that. Our job is to help shape the relationship between users and the Vue ecosystem. This ever-evolving guide provides some rules and recommendations on how to do that consistently within the Vue ecosystem. Principles A feature … Continue reading Documentation As Empathy
Messengers
It seems to me that some messaging app that has the functionality of WeChat is where a lot of this web3 and cryptocurrency is going. The functionality of WeChat is described by Wikipedia as: messaging, public accounts (for famous people or people with an audience), channels for friend groups, digital payments, video, etc. Right now, … Continue reading Messengers
Questions on Democracy & Ballots
What's the point of having a ballot with only one option and no write-in? Maybe offer abstain as the option? Why am I voting on judges and retaining judges? If you are going to make someone vote whether it is yes/no or no option, can we have a meta vote option where we select no … Continue reading Questions on Democracy & Ballots
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